000			01625pam a22002534a 4500
001			1285830
008			060824s2007 paua b 001 0 eng
020			_a9780781782104
020			_a0781782104
040			_aPGIMLl
041	0	9	_aeng
060			_aWA 20.5 _bD27 _2
245	0	0	_aDesigning clinical research _cStephen B. Hulley ... [et al.].
250			_a3rd ed.
260			_aPhiladelphia : _bWolters Kluwer Health/Lippincott Williams & Wilkins, _c2007.
300			_axv, 367 p. : _bill.
504			_aIncludes bibliographical references and index.
505	0		_aGetting started: the anatomy and physiology of clinical research -- Conceiving the research question -- Choosing the study subjects: specification, sampling, and recruitment -- Planning the measurements: precision and accuracy -- Getting ready to estimate sample size: hypotheses and underlying principles -- Estimating sample size and power: applications and examples -- Designing a cohort study -- Designing cross-sectional and case-control studies -- Enhancing causal inference in observational studies --
505	0		_aDesigning a randomized blinded trial -- Alternative trial designs and implementation issues -- Designing studies of medical tests -- Utilizing existing databases -- Addressing ethical issues -- Designing questionnaries and interviews -- Data management -- Implementing the study and quality control -- Community and international studies -- Writing and funding a research proposal.
650		0	_aPublic Health _9455 _xResearch Methodology
700			_aHulley, SB. _93137
942			_2lcc _cBK
999			_c1975 _d1975